Qualified for Round of 16
- Costa Rica (2)- Herediano, Saprissa
- Honduras (2)- Marathon, Olimpia
- Panama (2)- San Francisco, Tauro
- El Salvador (1)- Alianza
- Guatemala (1)- Municipal
- Nicaragua (1)- Real Esteli
- TBD (1)- Caribbean Championship runners up
Qualified for Preliminary Round
- El Salvador (2)- FAS, Municipal Limeno
- Guatemala (2)- Antigua GFC, Comunicaciones
- Belize (1)- Verdes
- Canada (1)- Forge FC
- Costa Rica (1)- Alajuelense
- Honduras (1)- Motagua
- Nicaragua (1)- Managua
- Panama (1)- Independiente
- TBD (2)- Caribbean Championship 3rd place, Caribbean playoff winners